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| |
T2DM women
|
Control women
|
P
|
|---|
|
n
|
132
|
55
| |
|
Age (years)
|
59.04 ± 12.61
|
57.0 ± 7.45
|
0.265
|
|
BMI (Kg/m2)
|
31.74 ± 5.94
|
28.38 ± 4.52
|
< 0.001
|
|
Waist circumference (cm)
|
100.03 ± 11.61
|
90.73 ± 14.87
|
0.0006
|
|
Smokers n (%)
|
17 (12.9)
|
6 (10.9)
|
0.29
|
|
Systolic blood pressure (mmHg)
|
134.39 ± 17.35
|
125.46 ± 12.75
|
0.0008
|
|
Diastolic blood pressure (mmHg)
|
78.52 ± 9.09
|
73.15 ± 9.38
|
0.0003
|
|
Diabetes duration (years)
|
7.77 ± 8.97
|
–
| |
|
HbA1c (%)
|
7.44 ± 1.44
|
–
| |
|
Fasting plasma glucose (mg/dl)
|
161.99 ± 50.03
|
96.75 ± 5.98
|
< 0.001
|
|
Insulin (mU/L)
|
16.38 ± 10.80
|
13.82 ± 10.11
|
0.68
|
|
HOMA-IR
|
6.86 ± 5.72
|
3.32 ± 2.46
|
0.0007
|
|
Creatinine (mg/dl)
|
0.89 ± 0.20
|
0.85 ± 0.10
|
0.114
|
|
eGFR (ml/min/1.73 m2)
|
68.27 ± 14.71
|
70.66 ± 10.32
|
0.273
|
|
Total cholesterol (mg/dl)
|
186.74 ± 29.64
|
201.00 ± 28.26
|
0.0016
|
|
HDL-cholesterol (mg/dl)
|
48.19 ± 13.69
|
53.76 ± 12.43
|
0.010
|
|
Triglycerides (mg/dl)
|
121.99 ± 59.92
|
99.78 ± 52.86
|
0.0341
|
|
LDL-cholesterol (mg/dl)
|
113.41 ± 26.50
|
127.29 ± 28.28
|
0.0032
|
|
LDL-C/HDL-C
|
2.70 ± 2.26
|
2.50 ± 0.84
|
0.522
|
|
Hypertension n (%)
|
87 (65.9)
|
18 (32.7)
|
< 0.001
|
|
CHD n (%)
|
36 (27.3)
|
0
|
–
|
|
Stroke/TIA
|
0
|
–
|
–
|
|
Carotid atherosclerosis (%)
|
34 (25.7)
|
–
|
–
|
|
Lower limb atherosclerosis (%)
|
24 (18.2)
|
–
|
–
|
|
Diabetic nephropathy n (%)
|
35 (26.5)
|
–
|
–
|
|
Diabetic retinopathy n (%)
|
30 (22.7)
|
–
|
–
|
|
Diabetic neuropathy n (%)
|
9 (6.8)
|
–
|
–
|
|
Insulin treatment n (%)
|
11 (8.3)
|
–
|
–
|
|
Oral Hypoglycaemic drugs n (%)
|
109 (82.6)
|
–
|
–
|
- Data are n, %, means ± DS
- eGFR: estimated glomerular filtration rate
- HOMA-IR: homeostatic model assessment
- Diabetic nephropathy:EGFR < 60 ml/min and/or albuminuria
