Articles

Pancreatic fat deposition is increased and related to beta-cell function in women with familial partial lipodystrophy

To study pancreatic fat deposition and beta-cell function in familial partial lipodystrophy (FPLD) patients.

Authors: Amelio F. Godoy-Matos, Cynthia M. Valerio, Rodrigo O. Moreira, Denise P. Momesso and Leonardo K. Bittencourt

Effects of moderate intensity endurance training vs. high intensity interval training on weight gain, cardiorespiratory capacity, and metabolic profile in postnatal overfed rats

Obesity is associated with several comorbidities, such as cardiovascular disease and type 2 diabetes mellitus, and may have its origin in early life stages, such as in the lactation period, through metabolic p...

Authors: Carlos Gabriel de Lade, Ana Eliza Andreazzi, Mariana Bolotari, Vinícius Moreira Gonçalves Costa, Vera Maria Peters and Martha de Oliveira Guerra

Nerve conduction study of the association between glycemic variability and diabetes neuropathy

It remains unclear whether glycemic variability is related to diabetes microvascular disease, especially diabetes peripheral neuropathy (DPN). We investigated the association between glycemic variability and D...

Authors: Miho Akaza, Itaru Akaza, Tadashi Kanouchi, Tetsuo Sasano, Yuki Sumi and Takanori Yokota

Characterization of spontaneously-developed non-alcoholic fatty liver disease in aged rhesus monkeys

Non-alcoholic fatty liver disease (NAFLD) is a global epidemic afflicting 20–30% in the general population. The animal model of NAFLD available at the present are less clinically relevant. In this study. We ai...

Authors: Wen Zheng, Yuli Liu, Haibao Shang, Yan Zhang, Dongwei Ma, Ning Hou, Jue Wang, Xueting Sun, Ying Peng, Lin Pan, Zhilong Wang, Xinran Tang, Rui-Ping Xiao and Xiuqin Zhang

Effectiveness of educational intervention based on psychological factors on achieving health outcomes in patients with type 2 diabetes

Managing type 2 diabetes (T2D) is assumed to be heavily dependent on patients’ active participation in their own self-care behaviors including prescribed diets.

Authors: Arash Salahshouri, Fereshteh Zamani Alavijeh, Behzad Mahaki and Firoozeh Mostafavi

Associations among inflammation, mental health, and quality of life in adults with metabolic syndrome

Metabolic syndrome (MetS), a pro-inflammatory state, has become increasingly common worldwide and is a major risk factor for type 2 diabetes mellitus and cardiovascular disease. Recently, studies on the relati...

Authors: Ji-Ryang Kim, Ha-Na Kim and Sang-Wook Song

Accuracy of insulin resistance indices for metabolic syndrome: a cross-sectional study in adults

This study aimed to determine the ability of commonly used insulin resistance indices to identify the metabolic syndrome.

Authors: Luciana Pavan Antoniolli, Bárbara Limberger Nedel, Tassia Cividanes Pazinato, Leonardo de Andrade Mesquita and Fernando Gerchman

Twice-daily insulin degludec/insulin aspart effectively improved morning and evening glucose levels and quality of life in patients previously treated with premixed insulin: an observational study

Previous studies comparing insulin degludec/insulin aspart (IDegAsp) with premixed insulin twice daily among insulin users with type 2 diabetes have not thoroughly investigated differences in the glucose varia...

Authors: Kanta Fujimoto, Toshio Iwakura, Megumi Aburaya and Naoki Matsuoka

Practical guidance for treatment of patients with diabetes using flash glucose monitoring: a pilot study

Flash glucose monitoring (FGM) is a factory-calibrated, blood glucose measuring sensor system for patients with diabetes. We aimed to investigate the correlation between the sensor glucose (SG) value obtained ...

Authors: Keiko Koide, Koichiro Azuma, Jun Nojima, Kenichiro Kodama and Yoshihito Atsumi

Association between the expression of vascular endothelial growth factors and metabolic syndrome or its components: a systematic review and meta-analysis

Several studies have linked vascular endothelial growth factors (VEGFs) with metabolic syndrome or its components. However, there has been no systematic appraisal of the findings of these studies to date. The ...

Authors: Mohammad Ishraq Zafar, Kerry Mills, Xiaofeng Ye, Brette Blakely, Jie Min, Wen Kong, Nan Zhang, Luoning Gou, Anita Regmi, Sheng Qing Hu, Juan Zheng and Lu-Lu Chen

Association between homocysteine level and the risk of diabetic retinopathy: a systematic review and meta-analysis

Previous studies have demonstrated that elevated homocysteine (Hcy) level represents an independent risk factor for macrovascular disease. However, the relationship between hyperhomocysteinemia and the progres...

Authors: Xunwen Lei, Guifeng Zeng, Yuemei Zhang, Qiang Li, Jinzhi Zhang, Zhenggang Bai and Kehu Yang

Normoalbuminuric kidney impairment in patients with T1DM: insights from annals initiative

We described, in a large sample of patients with type 1 diabetes mellitus (T1DM) and GFR ≤ 60 mL/min/1.73 m² (with or without albuminuria), the differences in the clinical features associated with the two differe...

Authors: Olga Lamacchia, Francesca Viazzi, Paola Fioretto, Antonio Mirijello, Carlo Giorda, Antonio Ceriello, Giuseppina Russo, Pietro Guida, Roberto Pontremoli and Salvatore De Cosmo

Markers of metabolic endotoxemia as related to metabolic syndrome in an elderly male population at high cardiovascular risk: a cross-sectional study

Metabolic syndrome (MetS) is a cluster of conditions that conjoined represents a 1.5–2.5 fold increased risk of developing cardiovascular disease (CVD). Recent studies have reported that gut dysbiosis and leak...

Authors: Ayodeji Awoyemi, Marius Trøseid, Harald Arnesen, Svein Solheim and Ingebjørg Seljeflot

The metabolic syndrome modifies the mRNA expression profile of extracellular vesicles derived from porcine mesenchymal stem cells

Mesenchymal stem cells (MSCs) perform paracrine functions by releasing extracellular vesicles (EVs) containing microRNA, mRNA, and proteins. We investigated the mRNA content of EVs in metabolic syndrome (MetS)...

Authors: Yu Meng, Alfonso Eirin, Xiang-Yang Zhu, Daniel R. O’Brien, Amir Lerman, Andre J. van Wijnen and Lilach O. Lerman

Impact of acute diabetes decompensation on outcomes of diabetic patients admitted with ST-elevation myocardial infarction

Acute hyperglycemia is associated with worse outcomes in diabetic patients admitted with ST-elevation myocardial infarction (STEMI). However, the impact of full-scale decompensated diabetes on STEMI outcomes h...

Authors: Mayada Issa, Fahad Alqahtani, Chalak Berzingi, Mohammad Al-Hajji, Tatiana Busu and Mohamad Alkhouli

A comparison of different definitions of metabolic syndrome for the risks of atherosclerosis and diabetes

The reported outcomes of the metabolic syndrome (MetS), containing atherosclerotic cardiovascular disease and diabetes, vary according to the definitions used. This study was designed to compare the performanc...

Authors: Sung-Sheng Tsai, Yun-Yi Chu, Szu-Tah Chen and Pao-Hsien Chu

Baseline and changes in serum uric acid independently predict glucose control among community-dwelling women

Elevated serum uric acid (SUA) levels are associated with glucose control. However, whether baseline and changes in SUA predict long-term follow-up glucose control [e.g., glycated hemoglobin (HbA1c)] remains u...

Authors: Ryuichi Kawamoto, Daisuke Ninomiya, Asuka Kikuchi, Taichi Akase and Teru Kumagi

Association of adiponectin with cognitive function precedes overt diabetes in the Brazilian Longitudinal Study of Adult Health: ELSA

Adiponectin is an insulin-sensitizer adipocytokine endowed with neuroprotective actions. Whether adiponectin regulates neuronal functioning toward delaying cognitive decline independently of the glucose metabo...

Authors: Adriana Cezaretto, Claudia Kimie Suemoto, Isabela Bensenor, Paulo A. Lotufo, Bianca de Almeida-Pititto and Sandra R. G. Ferreira

Smoke exposure and cardio-metabolic profile in youth with type 1 diabetes

To evaluate the relationship between smoking and metabolic parameters in patients affected by type 1 diabetes (T1D).

Authors: Valeria Calcaterra, Jonathan P. Winickoff, Catherine Klersy, Luca Maria Schiano, Rossella Bazzano, Chiara Montalbano, Valeria Musella, Corrado Regalbuto, Daniela Larizza and Hellas Cena

Association of dietary patterns with continuous metabolic syndrome in children and adolescents; a nationwide propensity score-matched analysis: the CASPIAN-V study

This study aims to determine the association of dietary patterns with metabolic syndrome (MetS) and its components in children and adolescents.

Authors: Roya Kelishadi, Ramin Heshmat, Marjan Mansourian, Mohammad Esmaeil Motlagh, Hasan Ziaodini, Majzoubeh Taheri, Zeinab Ahadi, Tahereh Aminaee, Azam Goodarzi, Morteza Mansourian, Mostafa Qorbani and Nafiseh Mozafarian

The effects of probiotic supplementation on metabolic status in type 2 diabetic patients with coronary heart disease

This study was conducted to evaluate the effects of probiotic supplementation on metabolic profiles in diabetic patients with coronary heart disease (CHD).

Authors: Fariba Raygan, Zohreh Rezavandi, Fereshteh Bahmani, Vahidreza Ostadmohammadi, Mohammad Ali Mansournia, Maryam Tajabadi-Ebrahimi, Shokoofeh Borzabadi and Zatollah Asemi

Associations of serum calcium levels and dietary calcium intake with incident type 2 diabetes over 10 years: the Korean Genome and Epidemiology Study (KoGES)

Previous evidence regarding the associations between serum calcium concentrations, dietary calcium intake, and type 2 diabetes (T2D) is limited. We investigated the longitudinal associations of serum calcium l...

Authors: Kyoung-Nam Kim, Se-Young Oh and Yun-Chul Hong

Optimal cut-off points for waist circumference in the definition of metabolic syndrome in Brazilian adults: baseline analyses of the Longitudinal Study of Adult Health (ELSA-Brasil)

Waist circumference (WC) has been incorporated in the definition of the metabolic syndrome (MetS) but the exact WC cut-off points across populations are not clear. The Joint Interim Statement (JIS) suggested p...

Authors: Thiane Ristow Cardinal, Alvaro Vigo, Bruce Bartholow Duncan, Sheila Maria Alvim Matos, Maria de Jesus Mendes da Fonseca, Sandhi Maria Barreto and Maria Inês Schmidt

Association between dietary protein intake and type 2 diabetes varies by dietary pattern

Epidemiological studies have demonstrated that high total protein intake was related to type 2 diabetes mellitus (T2DM) risks. However, few studies considered the impact of dietary pattern.

Authors: Qiuyi Ke, Chaogang Chen, Fengyi He, Yongxin Ye, Xinxiu Bai, Li Cai and Min Xia

Coenzyme Q10 suppresses apoptosis of mouse pancreatic β-cell line MIN6

In mitochondrial diabetes, apoptosis of β-cells caused by mitochondrial stress plays an important role in impaired insulin secretion. Several studies have reported that coenzyme Q10 (CoQ10) has therapeutic eff...

Authors: Keisuke Sumi, Tsuyoshi Okura, Youhei Fujioka, Masahiko Kato, Takeshi Imamura, Shin-ichi Taniguchi and Kazuhiro Yamamoto

Diabetic retinopathy among Brazilian Xavante Indians

To describe the frequency of diabetic retinopathy (DR) and its associated variables in Brazilian Xavante Indians.

Authors: Carlos Gustavo M. G. Lima, Laercio Joel Franco, Amaury L. Dal Fabbro, Edson Z. Martinez, João Paulo Botelho Veira-Filho, Alexandre A. C. M. Ventura, Leonardo Prevelato and Antonio Augusto V. Cruz

Predictors of 25-hydroxyvitamin D status among individuals with metabolic syndrome: a cross-sectional study

The risk of metabolic syndrome can be influenced by inadequate vitamin D levels, and exposure to sunlight is the main external source of vitamin D. The present study assessed the influence of environmental, bi...

Authors: Séphora Louyse Silva Aquino, Aline Tuane Oliveira da Cunha, Hermilla Torres Pereira, Erika Paula Silva Freitas, Ana Paula Trussardi Fayh, Josivan Gomes Lima, Severina Carla Vieira Cunha Lima, Karine Cavalcanti Maurício Sena-Evangelista and Lucia Fátima Campos Pedrosa

T allele at ADIPOQ rs1501299 G/T polymorphism is more susceptible to the influence of circulating adiponectin on arterial stiffness in nondiabetic men

Low adiponectin levels are associated with increased insulin resistance (IR) and arterial stiffness in hypertensive patients, but higher adiponectin levels are also found in heart failure patients. This discre...

Authors: Juhyun Song, So Ra Yoon and Oh Yoen Kim

Correction to: The prevalence and risk factors of peripheral neuropathy among patients with type 2 diabetes mellitus; the case of Jordan

It has been highlighted that the original article [1], published 21 February 2018, contained some errors in Table 3. This correction article shows the correct version of Table 3 and the changes that were made.

Authors: Nahla Khawaja, Jawad Abu-Shennar, Mohammed Saleh, Said S. Dahbour, Yousef S. Khader and Kamel M. Ajlouni

Assessing the added predictive ability of a metabolic syndrome severity score in predicting incident cardiovascular disease and type 2 diabetes: the Atherosclerosis Risk in Communities Study and Jackson Heart Study

The severity of the metabolic syndrome (MetS) predicts future coronary heart disease (CHD) and diabetes independent of the individual MetS components. Our aim was to evaluate whether MetS severity conferred ad...

Authors: Yi Guo, Solomon K. Musani, Mario Sims, Thomas A. Pearson, Mark D. DeBoer and Matthew J. Gurka

Adipose tissue-derived cytokines and their correlations with clinical characteristics in Vietnamese patients with type 2 diabetes mellitus

Adipokines are involved in the pathogenesis of metabolic disorders including obesity and type 2 diabetes mellitus (T2DM). This study investigates the levels of leptin, resistin, visfatin, secreted frizzled-rel...

Authors: Nguyen Linh Toan, Nguyen Van Hoan, Doan Viet Cuong, Nguyen Viet Dung, Phan The Dung, Ngo Thu Hang, Do Thi Huyen Dieu, Dang Thanh Chung, Ho Anh Son, Pham Xuan Phong, George Binh Lenon, Doan Van De and Hoang Van Tong

Higher cardiometabolic risk in idiopathic versus autoimmune type 1 diabetes: a retrospective analysis

Idiopathic type 1 diabetes mellitus (IDM) is characterized by an onset with insulinopenia and ketoacidosis with negative β-cell autoimmunity markers and lack of association with HLA. The aim of the study is to...

Authors: Valentina Guarnotta, Enrica Vigneri, Giuseppe Pillitteri, Alessandro Ciresi, Giuseppe Pizzolanti and Carla Giordano

The effectiveness of stress management training on blood glucose control in patients with type 2 diabetes

Type 2 diabetes is a chronic disease that is expanding at an alarming rate in the world. Research on individuals with type 2 diabetes showed that stressful life events cause problems in the effective managemen...

Authors: Fereshteh Zamani-Alavijeh, Marzieh Araban, Hamid Reza Koohestani and Mahmood Karimy

Improved insulin sensitivity and lower postprandial triglyceride concentrations after cold-pressed turnip rapeseed oil compared to cream in patients with metabolic syndrome

The aim of this study was to compare acute effects of turnip rapeseed oil rich with mono- and polyunsaturated fatty acids and cream on postprandial triglyceride levels and post-glucose load measures of insulin...

Authors: Harri Juhani Saarinen, Sari Husgafvel, Hanna Pohjantähti-Maaroos, Marja Wallenius and Ari Palomäki

TCF7L2 correlation in both insulin secretion and postprandial insulin sensitivity

The TCF7L2 rs7903146 variant is strongly associated with type 2 diabetes mellitus (T2DM). However, the mechanisms involved in this association remain unknown and may include extrapancreatic effects. The aim of th...

Authors: Mari Cassol Ferreira, Maria Elizabeth Rossi da Silva, Rosa Tsuneshiro Fukui, Maria do Carmo Arruda-Marques and Rosa Ferreira dos Santos

Establishing post mortem criteria for the metabolic syndrome: an autopsy based cross-sectional study

Individuals who suffer from mental illness are more prone to obesity and related co-morbidities, including the metabolic syndrome. Autopsies provide an outstanding platform for the macroscopic, microscopic and...

Authors: Martin Roest Christensen, Anne Bugge, Mariam Elmegaard Malik, Jørgen Lange Thomsen, Niels Lynnerup, Jørgen Rungby and Jytte Banner

Post-operative stress hyperglycemia is a predictor of mortality in liver transplantation

A significant association is known between increased glycaemic variability and mortality in critical patients. To ascertain whether glycaemic profiles during the first week after liver transplantation might be...

Authors: Elena Giráldez, Evaristo Varo, Ipek Guler, Carmen Cadarso-Suarez, Santiago Tomé, Patricia Barral, Antonio Garrote and Francisco Gude

Metabolic syndrome among overweight and obese adults in Palestinian refugee camps

Metabolic syndrome (MetS) is one of the main reasons for elevated cardiovascular morbidity and mortality worldwide. Obese and overweight individuals are at high risk of developing these chronic diseases. The a...

Authors: Basma Damiri, Mohammed S. Abualsoud, Amjad M. Samara and Sakhaa K. Salameh

Hookah smoking is strongly associated with diabetes mellitus, metabolic syndrome and obesity: a population-based study

The adverse effects of cigarette smoking have been widely studied before, whilst the effects of hookah smoking has received less attention, although it is a common habit in the Middle East. Here we have invest...

Authors: Sara Saffar Soflaei, Susan Darroudi, Maryam Tayefi, Abolfazl Nosrati Tirkani, Mohsen Moohebati, Mahmoud Ebrahimi, Habibollah Esmaily, Seyed Mohammad Reza Parizadeh, Ali Reza Heidari-Bakavoli, Gordon A. Ferns and Majid Ghayour-Mobarhan

Chikungunya and diabetes, what do we know?

Chikungunya (CHIK) is a viral disease transmitted by mosquitoes. The first cases in Brazil were confirmed in 2014. Between 2016 and 2017, over 300,000 cases were identified during this period, with nearly 300 ...

Authors: Francisca Kalline de Almeida Barreto, Renan Magalhães Montenegro Jr., Virginia Oliveira Fernandes, Rhaquel Oliveira, Lívia Aline de Araújo Batista, Akhtar Hussain and Luciano Pamplona de Góes Cavalcanti

Possible neuroprotective role of P2X2 in the retina of diabetic rats

Purinergic receptors are expressed in different tissues including the retina. These receptors are involved in processes like cell growth, proliferation, activation and survival. ATP is the major activator of P...

Authors: Jorge E. Mancini, Gustavo Ortiz, Constanza Potilinstki, Juan P. Salica, Emiliano S. Lopez, J. Oscar Croxatto and Juan E. Gallo

21st Brazilian Diabetes Society Congress

Authors:

Effectiveness of gliclazide MR 60 mg in the management of type 2 diabetes: analyses from the EASYDia trial

Although the number of antihyperglycemic agents has expanded significantly, sulfonylureas (in particular gliclazide) remain an important option because of a variety of patient and health system factors. The la...

Authors: Lawrence A. Leiter, Marina V. Shestakova and Ilhan Satman

Association of mean platelet volume with incident type 2 diabetes mellitus risk: the Dongfeng–Tongji cohort study

Most of prior studies to demonstrate the association between mean platelet volume (MPV) and type 2 diabetes mellitus (T2DM) risk were cross-sectional design with inconsistent results. In the present prospectiv...

Authors: Zhaoyang Li, Jing Wang, Xu Han, Jing Yuan, Huan Guo, Xiaomin Zhang, Dan Zheng, Yuhan Tang, Handong Yang and Meian He

The impact of a disease management programme for type 2 diabetes on health-related quality of life: multilevel analysis of a cluster-randomised controlled trial

Type 2 diabetes is a chronic disease associated with poorer health outcomes and decreased health related quality of life (HRQoL). The aim of this analysis was to explore the impact of a disease management prog...

Authors: Sigrid Panisch, Tim Johansson, Maria Flamm, Henrike Winkler, Raimund Weitgasser and Andreas C. Sönnichsen

Combination of basal insulin and GLP-1 receptor agonist: is this the end of basal insulin alone in the treatment of type 2 diabetes?

Glycemic control has been considered a major therapeutic goal within the scope of diabetes management, as supported by robust observational and experimental evidence. However, the coexistence of micro and macr...

Authors: Rodrigo Oliveira Moreira, Roberta Cobas and Raquel C. Lopes Assis Coelho

Sarcopenia: a chronic complication of type 2 diabetes mellitus

Diabetics are at increased risk for impaired mobility and strength, frequently related to the disease control. Sarcopenia is the reduction of muscle mass associated with the decrease in muscle strength and/or ...

Authors: Heloísa Trierweiler, Gabrielle Kisielewicz, Thaísa Hoffmann Jonasson, Ricardo Rasmussen Petterle, Carolina Aguiar Moreira and Victória Zeghbi Cochenski Borba

Dynamic development of metabolic syndrome and its risk prediction in Chinese population: a longitudinal study using Markov model

With the increasing prevalence of metabolic syndrome (MS), there is a need to track and predict the development of MS. In this study, we established a Markov model to explore the natural history and predict th...

Authors: Xiaoxian Jia, Qicai Chen, Peipei Wu, Meng Liu, Xiaoxiao Chen, Juan Xiao, Lili Chen, Pengpeng Zhang and Shumei Wang

Bridging glycated hemoglobin with quality of life and health state; a randomized case–control study among type 2 diabetes patients

The aim of this study was to explore the predictors of QOL and health state and examine the relationship with glycemic control among type 2 diabetes mellitus (T2DM) patients.

Authors: Syed Wasif Gillani, Irfan Altaf Ansari, Hisham A. Zaghloul, Mohi Iqbal Mohammad Abdul, Syed Azhar Syed Sulaiman and Mirza R. Baig

Relationship between “a body shape index (ABSI)” and body composition in obese patients with type 2 diabetes

Obesity is known to be related to the development of type 2 diabetes mellitus (T2D). The most commonly used anthropometric indicator (body mass index [BMI]) presents several limitations such as the lack of pos...

Authors: Fernando Gomez-Peralta, Cristina Abreu, Margarita Cruz-Bravo, Elvira Alcarria, Gala Gutierrez-Buey, Nir Y. Krakauer and Jesse C. Krakauer